UNIchip® Antibody Characterisation

 

UNIchip® family of Protein Biochips

Protagen AG has developed the UNIchip® family of protein biochips for faster development of diagnostic and therapeutic antibodies or other protein binders.

The UNIchip® biochips are printed with 400 recombinant human proteins in a proprietary layout enabling quantitative analysis of antibody binding.

In the UNIchip® Premium version customer-supplied proteins (e.g. cognate antigens) are printed as a serial dilution for affinity ranking and as positive controls.

The unique line of protein biochips is suitable for the following applications:

  • Antibody specificity analysis for predicting performance in immuno-histochemistry
  • Quantitative antibody fingerprint generation for development, production and quality control purposes
  • Determination of "off-target-activity" of antibodies
  • Affinity ranking of antibodies
  • Selection of antibody pairs for ELISA-Development

The following protein biochips are available from the UNIchip® AV-series:

  • UNIchip® AV-400                (cross section of cellular proteins)
  • UNIchip® AV-VAR EP         (extracellular proteins) 
  • UNIchip® AV-VAR MP         (membrane proteins)
  • UNIchip® AV-VAR IP           (intracellular proteins)

An easy to use UNIchip® Data Analysis Tool generates quantitative antibody binding profiles (fingerprints) and binding curves in a standardized format.

 

UNIchip® Services

Efficient evaluation of the UNIchip® products is possible through the complete service package. Talk to the experts of Protagen to discuss the optimal study design and customisation options for your research program.

 

Further information:

 

Sensitivity PB brochure Linearity, sensitivity and dynamic range of three different antibodies targeted against the same antigen.

OTA PB brochureQuantitative antibody fingerprint based on 400 different human proteins.
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