High-end differential display and analysis of proteomes

The differential quantitative analysis and identification of the total protein set of a biological system provides new insights into the molecular coherences and functional protein networks. The knowledge gained through proteome analysis can be used in many ways. Fermentation processes can be optimized, relevant biomarkers can be identified, and the information content of in-vitro and in-vivo pharmacology studies can be significantly enhanced.

Important factors for a successful study by differential protein display are:

  • Study design
  • optimization of sampling
  • statistical evaluation

Protagen chooses from a portfolio of methods to create the optimal study for your samples, such as:

  • High-resolution 2D PAGE analysis with up to 40x30cm gel
  • Solubilisation and separation of membrane proteomes 
  • Fluorescent labelling techniques for the analysis of smallest sample amounts
  • LC-ESI-MS analysis with highest mass accuracy
  • Label-free relative quantification
  • Labelled samples for relative quantification
  • Absolute quantification by AQUA

Please This e-mail address is being protected from spambots. You need JavaScript enabled to view it Protagen to design a study tailored to your needs.

 

Further information:

Identification of relevant differences in protein expression

 

 Typical workflow of a proteome study

 

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