Technologies

UNIarray^® for the Development of Diagnostics

As an innovator in protein biochips, Protagen has developed UNIarray^®, a technology platform for the development of diagnostics.
UNIarray^® allows the systematic identification of proprietary autoantibody signatures in blood for the development of new diagnostics and companion diagnostics for patient stratification and therapy selection. Indications like autoimmune diseases, cancer, inflammatory diseases and neurodegenerative disorders have been addressed successfully in internal discovery and development programs.
The UNIarray^® technology platform is based on a patent-protected technology platform originally developed at the Max-Planck-Institute for Molecular Genetics in Berlin, Germany.
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Protein Biochips

As an innovator in protein biochips, Protagen has developed UNIchip^®, a versatile and highly efficient series of protein microarrays for faster antibody development. Particular with regard to faster selection of the best candidate for further development by quantitative ranking of the specificity and sensitivity of antibodies, the UNIchip^® platform provides a cost efficient and reliable concept.
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Cutting Edge Protein Analysis

Protagen AG features a wide range of state-of-the-art analytical methods. They include (among others) mass spectrometry for peptide mapping, N- and C-terminal sequencing and intact mass determination, HPLC separation of glycans and proteins, electrophoretic separations using large format 2D Gels and amino acid analysis. The strong expertise in bioinformatics allows us to mine the data sets to the greatest extent, ensuring a maximum return of information.
The end result is the proven quality of the products and services we have provided to our customers internationally.
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GMP compliant Protein Analysis

Protagen AG is a GMP certified laboratory for protein analysis and release testing. We are actively supporting our customers in the development of new analytical methods as well as in the analysis of drug substances or drug products using pharmacopeia methods. Our strong scientific background allows us to provide very efficient solutions for our customers. We strive to support our customers in all stages of the drug development process.
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Bio-IT in Proteomics

Protagen has a long background in proteomics data interpretation and is developing various algorithms and software solutions for proteomics.
Among those efficient algorithms for Image Spot Detection/Image Warping, Data Calibration, Peak Detection, Noise Reduction, Normalisation, Spectrum/LC-MS Run Classification, RT Alignment, Peptide Identification, PTM Discovery, Protein Identification and Metascoring are developed.
The knowledge and expertise in design and implementation of labor information management systems (LIMS) for inhouse solutions as well as for software products is bringing wet lab data acquisition to knowledge discovery.
The outstanding expertise in understanding lab applications and modern software development at the same time makes the Bio-IT know how at Protagen unique. This resource is available to our customers in a very flexible and tailored service model.
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